🎞 MTDbBest ofBy yearBy genreBy runtimeBrowse (app)

MTDb › Best of › 2010 › Splice

Splice poster

Splice (2010)

“She's not human...not entirely.”

5.9/10 · 2,518 votes 1h 44m r HorrorScience-fiction

#211 of 247 films from 2010 #934 of 1243 in horror

Directed by Vincenzo Natali · Written by Vincenzo Natali, Doug Taylor, Antoinette Terry Bryant

▶ Trailer, images & where to stream

Overview

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Cast

Adrien Brodyas Clive
Sarah Polleyas Elsa
Delphine Chanéacas Dren
David Hewlettas Barlow
Abigail Chuas Young Dren
Stephanie Bairdas Elsa / PD
Brandon McGibbonas Gavin
Amanda Brugelas Melinda Finch
Simona Măicănescuas Joan Chorot

Facts

Release dateJune 3, 2010
Runtime104 min (1h 44m) — about the same as the 2010 average of 104 min
GenresHorror, Science-fiction
LanguageEN
Budget$26,000,000
IMDbtt1017460

More from Vincenzo Natali

Paris Je T'aimeParis Je T'aime2006 · ★ 6.8 · 2h 0m CubeCube1998 · ★ 6.8 · 1h 30m CypherCypher2002 · ★ 6.6 · 1h 35m HaunterHaunter2013 · ★ 6.1 · 1h 37m In the Tall GrassIn the Tall Grass2019 · ★ 5.6 · 1h 41m

If you liked Splice

Same genre, released within a few years, sorted by TMDB rating.

A Quiet PlaceA Quiet Place2018 · ★ 7.4 · 1h 31m Justice League DarkJustice League Dark2017 · ★ 7.3 · 1h 16m Shin GodzillaShin Godzilla2016 · ★ 7.2 · 2h 0m 28 Days Later28 Days Later2002 · ★ 7.2 · 1h 53m Dawn of the DeadDawn of the Dead2004 · ★ 7.1 · 1h 41m 10 Cloverfield Lane10 Cloverfield Lane2016 · ★ 7.0 · 1h 44m The MistThe Mist2007 · ★ 7.0 · 2h 6m The HostThe Host2006 · ★ 7.0 · 2h 0m

Questions

How long is Splice?
Splice runs 104 minutes (1h 44m).
Is Splice worth watching?
TMDB users give it 5.9/10 across 2,518 votes, which places it #211 of 247 films released in 2010 in this index (top 15%) and #934 among 1243 horror titles.
Who directed Splice?
Splice was directed by Vincenzo Natali. Other well-rated titles by the same director: Paris Je T'aime (2006), Cube (1998), Cypher (2002).
Who stars in Splice?
Adrien Brody as Clive; Sarah Polley as Elsa; Delphine Chanéac as Dren; David Hewlett as Barlow; Abigail Chu as Young Dren; Stephanie Baird as Elsa / PD.
What is Splice rated?
It carries a r certification in its home market. Ratings differ by country.
Where can I watch the trailer for Splice?
Open the title in the MTDb app for trailers, images and streaming links: https://mv.peoplentools.com/titles/109799.

Browse

Best of 2010Best horrorHorror of the 2010sBest science-fictionScience-fiction of the 2010sAll lists
MTDb·Best films by year, genre and runtime·A century in numbers·Browse and watch trailers

Film data and images from TMDB. This product uses the TMDB API but is not endorsed or certified by TMDB. Ratings are TMDB user scores as of 2026-10-05.